Longevity hormone boosts memory and protects against brain aging in mice
This illustration exhibits how klotho therapy in mice quickly improved studying and reminiscence of a hidden platform in a water maze. Credit score: Leon et al. In a research that augurs properly for the therapeutic potential of klotho -- a life-extending protein hormone minority of individuals naturally produce at excessive ranges -- scientists at UC San Francisco have discovered that administering a fraction of the klotho protein to younger, getting old or impaired mice quickly improves their cognitive and bodily efficiency. Whereas earlier research had revealed associations between elevated klotho ranges and higher cognition, that analysis had been accomplished with mice genetically engineered to constantly produce excessive klotho ranges and in folks carrying genetic variants that induced them to have excessive klotho ranges all through life. Because of this, it was nonetheless unclear whether or not klotho could possibly be administered like a drug to quic...